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Assistant Professor Nontaphat Leerach, Ph.D. is an academic and researcher specializing in microbial immunology, with a primary focus on host–microbe interactions, macrophage dysfunction, and immunosenescence. His research investigates how pathogenic microorganisms and environmental stressors influence immune-cell function, particularly within the innate immune system. His work integrates microbiology, immunology, and pharmacology to investigate the molecular mechanisms underlying inflammation, cellular senescence, and immune dysfunction. Particular emphasis is placed on RAGE–NF-κB signaling, macrophage dysfunction, and senescence-associated inflammation. His current research also explores bacterial extracellular vesicles, postbiotics, natural bioactive compounds, and small molecules as potential immunomodulatory strategies for restoring immune function and regulating inflammation.
ประวัติการศึกษา
2013
Naresuan University, Thailand Bachelor of Science (B.Sc.) with Honors, Microbiology (Research Field: Molecular Bacteriology and Immunology)
2016
Naresuan University, Thailand Master of Science (M.Sc.), Pharmacology (Research Field: Molecular Biology and Regenerative Medicine)
2021
Kanazawa University, Japan Doctor of Philosophy (Ph.D.), Medical Sciences Research field: Molecular Immunology (Research Field: Molecular and cellular Immunology)
งานวิจัยและตีพิมพ์วารสาร
งานวิจัยที่น่าสนใจ
- Microbial Immunology and Host–Microbe Interactions
- Macrophage Biology, Dysfunction, and Immunosenescence
- Bacterial Extracellular Vesicles and Microbial Immunomodulation
- RAGE–NF-κB Signaling and Inflammatory Regulation
- Antimicrobial Resistance and Host Defense
- Postbiotics, Natural Products, and Small-Molecule Immunomodulators
ผลงานตีพิมพ์
ผลงานวิชาการ
2026
Nakyai W, Chatsirisupachai A, Thamsermsang O, Sonthi P, Yamamoto Y, Leerach N*. Salacia chinensis leaf extract suppresses RAGE-mediated NF-κB activation in human RAGE-expressing C6 glioma cells. Presented at the 9th International Conference and Exhibition on Pharmaceutical Sciences and Technology (PST 2026); June 25–26, 2026; Bangkok, Thailand. *Corresponding author.
2025
Suppramote O, Leerach N, Dejakaisaya H, Prasopporn S, Buraphat P, Makjaroen J, Yamamoto Y, Harashima A, Munesue S, Jirawatnotai S. Exploring anti-angiogenic drug repurposing as a synergistic approach with CDK4/6 inhibitors in cholangiocarcinoma. Poster presented at the 84th Annual Meeting of the Japanese Cancer Association (JCA2025); September 25–27, 2025; Kanazawa, Japan.
2026
Platinum Award The 9th International Conference and Exhibition on Pharmaceutical Sciences and Technology (PST 2026), Bangkok, Thailand
2025
Follow-up Research Fellowship Japan Student Services Organization (JASSO), Japan
2017
Japanese Government (MEXT) Scholarship Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan
2016
Boosting Research Potential Program University of Tübingen, Germany
2014
Graduate School Full Scholarship Naresuan University, Thailand
2014
Research Assistantship Center of Excellence for Innovation in Chemistry (PERCH-CIC), Thailand
2013
International Cooperative Education Scholarship Faculty of Medicine, Universiti Malaya, Malaysia
Professional Training
2025
Visiting Researcher, Kanazawa University Graduate School of Medical Sciences, Japan
2021–2022
Postdoctoral Research Fellow, Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Sciences, Japan
2016
Visiting Scholar, Faculty of Medicine, Eberhard Karls University of Tübingen, Germany
2013
Research Intern, Molecular Microbiology and Parasitology, Faculty of Medicine, Universiti Malaya, Malaysia